Gas chromatographic determination of isosorbide dinitrate in human plasma and urine |
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Authors: | Ntoine Sioufi,Fran oise Pommier |
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Affiliation: | Ntoine Sioufi,Françoise Pommier |
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Abstract: | A rapid, simple and sensitive method for the specific determination of isosorbide dinitrate concentrations down to 0.5 ng/ml in human plasma and urine is described. Following traction (with or without internal standard) of isosorbide dinitrate into toluene, the compound is determined by gas chromatography using a 63Ni electron-capture detector. |
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