Topography of nucleic acid helices in solutions. XXIV. Intercalation specificities of DNA and their possible role in the recognition process

Through the use of reporter molecules, I, it is shown that more than one type of intercalating site must exist in DNA. Although this finding is completely consistent with the DNA structure it has not yet been demonstrated. The significance of the presence of different intercalating sites in DNA may be of extreme importance in the recognition of nucleic acid-protein systems.