The influence of the cation of quaternized chitosans on antioxidant activity |
| |
Authors: | Jingli Liu Huili Sun Fang Dong Qinzhao Xue Gang Wang Song Qin Zhanyong Guo |
| |
Institution: | aYantai Institute of Coastal Zone Research for Sustainable Development, Chinese Academy of Sciences, Yantai 264003, China;bInstitute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China;cGraduate School of Chinese Academy of Sciences, Beijing 100039, China;dSouth China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China |
| |
Abstract: | Various quaternized chitosans (QCSs) were synthesized according to previous method. Their reducing power and antioxidant potency against hydroxyl radicals (OH) and hydrogen peroxide (H2O2) were explored by the established systems in vitro. The QCSs exhibited markedly antioxidant activity, especially TCEDMCS, whose IC50 on hydroxyl radicals was 0.235 mg/mL. They showed 65–80% scavenging effect on hydrogen peroxide at a dose of 0.5 mg/mL. Generally, the antioxidant activity decreased in the order TCEDMCS > TBEDMCS > EDMCS > PDMCS > IBDMCS > Chitosan. Furthermore, the order of their OH and H2O2 scavenging activity was consistent with the electronegativity of different substituted groups in the QCSs. The QCSs showed much stronger antioxidant activity than that of chitosan may be due to the positive charge density of the nitrogen atoms in QCSs strengthened by the substituted groups. |
| |
Keywords: | Quaternized chitosans Antioxidant activity Group electronegativity |
本文献已被 ScienceDirect 等数据库收录! |
|