E-cadherin expression and bromodeoxyuridine incorporation during development of ovarian inclusion cysts in age-matched breeder and incessantly ovulated CD-1 mice |
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| Authors: | Jean S Fleming H James McQuillan Melanie J Millier Clare R Beaugié Vicki Livingstone |
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| Institution: | (1) Eskitis Institute of Cell & Molecular Therapies, Griffith University Nathan campus, QLD, 4111 Nathan, Australia;(2) Department of Anatomy and Structural Biology, University of Otago School of Medical Sciences, PO Box 913, Dunedin, New Zealand;(3) Department of Preventive & Social Medicine, University of Otago Health Sciences, PO Box 913, Dunedin, New Zealand |
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| Abstract: | Background Female CD-1/Swiss Webster mice subjected to incessant ovulation for 8 months and 12-month breeder mice both developed ovarian
inclusion cysts similar to serous cystadenomas. The majority of cysts appeared to be dilated rete ovarii tubules, but high
ovulation number resulted in more cortical inclusion cysts. We hypothesized that comparison of inclusion cyst pathology in
animals of the same age, but with differences in total lifetime ovulation number, might allow us to determine distinguishing
characteristics of the two types of cyst. |
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