Genomic and proteomic profiling II: Comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars |
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| Authors: | Xiaoping Luo Qun Pan Li Liu Nasser Chegini |
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| Affiliation: | (1) Department of Obstetrics and Gynecology, University of Florida, College of Medicine, 32610 Gainesville, Florida, USA;(2) Interdisciplinary Center for Biotechnology Research, University of Florida, College of Medicine, 32610 Gainesville, Florida, USA |
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| Abstract: | Background Leiomyoma have often been compared to keloids because of their fibrotic characteristic and higher rate of occurrence among African Americans as compared to other ethnic groups. To evaluate such a correlation at molecular level this study comparatively analyzed leiomyomas with keloids, surgical scars and peritoneal adhesions to identify genes that are either commonly and/or individually distinguish these fibrotic disorders despite differences in the nature of their development and growth. |
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