| 胃溃疡对大鼠胃中HAP1表达的影响 |
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| 引用本文： | 许瑞娜,柯辉,邹峰,王立. 胃溃疡对大鼠胃中HAP1表达的影响[J]. 氨基酸和生物资源, 2006, 28(4): 59-61. DOI: 10.3969/j.issn.1006-8376.2006.04.016 |
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| 作者姓名： | 许瑞娜 柯辉 邹峰 王立 |
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| 作者单位： | 湖北中医学院解剖与组胚教研室,武汉,430061 |
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| 摘 要： | 建立冰乙酸性大鼠胃溃疡模型,采用ABC法进行免疫组织化学染色,观察并探讨胃溃疡对胃壁中HAP1(huntingtin as-soc iated protein 1,HAP1)表达的影响。结果溃疡组大鼠胃壁中HAP1阳性细胞数目及光密度与正常进食的大鼠相比显著增多。
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| 关 键 词： | 享廷顿蛋白相关蛋白1(HAP1) 胃溃疡 |
| 文章编号： | 1006-8376(2006)04-0059-03 |
| 收稿时间： | 2006-11-07 |
| 修稿时间： | 2006-11-07 |
Effect of HAP1 on Rat Gastric Ulcer |
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| XU Rui-na,KE Hui,ZOU Feng,WANG Li. Effect of HAP1 on Rat Gastric Ulcer[J]. Amino Acids & Biotic Resources, 2006, 28(4): 59-61. DOI: 10.3969/j.issn.1006-8376.2006.04.016 |
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| Authors: | XU Rui-na KE Hui ZOU Feng WANG Li |
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| Affiliation: | Division of Anatomy and Histology and Embryology, Hubei Chinese Medical College, Wuhan 430061 China |
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| Abstract: | Whether huntingtin associated protein 1(HAP1) is localized in the mucosa of the rat and HAP1 is involved in gastric ulcer was investigated.ABC method of immunohistochemistry was used to observe the localizing feature of HAP1 in the stomach of the rat and the effect of gastric ulcer on expressing of HAP1 in the stomach.It was found that HAP1 was distributed in the mucosa of the stomach of rats.The HAP1 positive cells increased in both number and intensity in gastric ulcer rats by immunohistochemistry.HAP1 is likely to play important roles in gastric ulcer. |
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| Keywords: | huntingtin associated protein 1 gastric ulcer rat |
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