Cost-effective production of <Emphasis Type="Italic">Bacillus licheniformis</Emphasis> using simple netting bag solid bioreactor |
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Authors: | Shumiao Zhao Ling Deng Nan Hu Bin Zhao Yunxiang Liang |
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Institution: | (1) State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, People’s Republic of China |
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Abstract: | A novel simple solid state fermentation method, netting bag bioreactor (Φ 120 × 800 mm), was developed and used to cultivate
Bacillus licheniformis as probiotics. High spore yield (1.2 × 1011 CFU/g dry substrate) has been obtained by using this method. Comparing to the tray bioreactor and the packed bed bioreactor
for Bacillus fermentation, the netting bag method was more cost-effective, time- and space-saving and the material cost is also as low
as ca. US $293 per 1,000 kg spores. Thus, netting bag SSF can be widely applied to produce probiotic bacteria in developing
areas. |
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Keywords: | Bacillus licheniformis Cost-effective production Probiotics Solid state fermentation Netting bag |
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