The effects of magnesium, calcium and EDTA on slime production byStaphylococcus epidermidis strains |
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Authors: | N Özerdem Akpolat S Elçi S Atmaca H Akbayin K Gül |
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Institution: | Department of Microbiology, Faculty of Medicine, University of Dicle, Diyarbakir, Turkey. nakpolat@dicle.edu.tr |
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Abstract: | Effect of magnesium, calcium and EDTA on slime production by 15 slime-positive and 13 slime-negative Staphylococcus epidermidis strains isolated from various clinical specimens was determined. The slime production on tryptic soy broth was significantly enhanced after addition of 128 mumol/L Mg2+. Similarly, the addition of Ca2+ caused a significant increase in slime production of all tested strains when concentration of Ca2+ exceeded 64 mumol/L. In contrast, in the presence of EDTA the slime production by all strains was significantly reduced. Hence Ca2+ and Mg2+ increase slime production of S. epidermidis. This finding is important in the context of the pathogenesis of biomedical implant infections caused by S. epidermidis. |
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