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Ribosomal resistance of an istamycin producer, Streptomycestenjimariensis, to aminoglycoside antibiotics
Authors:Hirokazu Yamamoto  Kunimoto Hotta  Yoshiro Okami  Hamao Umezawa
Affiliation:Institute of Microbial Chemistry 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan
Abstract:Streptomycestenjimariensis SS-939 was resistant to its own aminoglycoside antibiotics, istamycins, as well as kanamycin A, neamine, ribostamycin and butirosin A, but was susceptible to neomycin B, lividomycin A and streptomycin. This resistance to these antibiotics was found to be due to ribosomes of the strain.
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