Sulfation and molecular weight of fibronectin shed by human melamona cells |
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| Authors: | Barry S Wilson Giovanna Ruberto Soldano Ferrone |
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| Institution: | The Department of Molecular Immunology Scripps Clinic and Research Foundation 10666 North Torrey Pines Road La Jolla, California 92037 USA |
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| Abstract: | Intrinsic radiolabeling, affinity chromatography and sodium dodecyl sulfate polyacrylamide gel electrophoresis of fibronectin shed by cultured human melanoma cells unexpectedly showed that it is sulfated and has a higher apparent molecular weight than plasma fibronectin. The implications of these findings are discussed. |
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