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The functional characteristics of the inhibitory mediator systems in the brain synaptosomes of PP vitamin-deficient rats] |
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| Authors: | A I Fomenko G V Chichkovskaia P K Parkhomets G V Donchenko S P Stepanenko A A Khalmuradov |
| Abstract: | A decrease of the NAD and serotonin level in the brain of rats with PP hypovitaminosis is shown. NAD in concentration of 10(-6) M in vitro exerts a less pronounced inhibiting influence on the neuronal uptake of 14C]serotonin and 14C]GABA by brain synaptosomes of rats with PP hypovitaminosis. GABA content under such conditions increases as compared with the control and correlates with changes in the 14C]GABA uptake system. |
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