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Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy |
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| Authors: | Anastasiia Filippova Julie Charles Olivier Epaulard Raphaële Germi Virginie Persoons Isabelle Templier Marie-Therese Leccia Brigitte Dreno Irina Malova Patrice Morand Julien Lupo |
| Abstract: | Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy. |
| Keywords: | Human herpesvirus 6 (HHV-6) immunotherapy tumor-infiltrating T lymphocyte therapy (TIL) reinfection |
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