The past,present and future of genome-wide re-annotation |
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| Authors: | Christos A Ouzounis Peter D Karp |
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| Institution: | (1) Computational Genomics Group, The European Bioinformatics Institute, EMBL Cambridge Outstation, CB10 1SD Cambridge, UK;(2) Bioinformatics Research Group, AI Center, SRI International, 94025 Menlo Park, CA, USA |
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| Abstract: | Annotation, the process by which structural or functional information is inferred for genes or proteins, is crucial for obtaining value from genome sequences. We define the process of annotating a previously annotated genome sequence as 're-annotation', and examine the strengths and weaknesses of current manual and automatic genome-wide re-annotation approaches. |
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