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LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse |
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| Authors: | Elaine M. Quinet Michael D. Basso Anita R. Halpern David W. Yates Robert J. Steffan Valerie Clerin Christine Resmini James C. Keith Thomas J. Berrodin Irene Feingold Wenyan Zhong Helen B. Hartman Mark J. Evans Stephen J. Gardell Elizabeth DiBlasio-Smith William M. Mounts Edward R. LaVallie Jay Wrobel Ponnal Nambi George P. Vlasuk |
| Affiliation: | *Department of Cardiovascular/Metabolic Diseases and Nuclear Receptor Biology, Wyeth Research, Collegeville, PA and Cambridge, MA;†Department of Bioresources, Wyeth Research Pearl River, NY;§Chemical Sciences, Wyeth Research, Collegeville, PA;**Department of Biotransformation, Wyeth Research, Collegeville, PA;††Department of Biological Technologies, Wyeth Research, Cambridge, MA |
| Abstract: | |
| Keywords: | cynomolgus monkey dyslipidemia fibroblast growth factor 19 hypertriglyceridemia |
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