Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery

Authors:	Joel A Kooren Nelson L Rhodus Chuanning Tang Pratik D Jagtap Bryan J Horrigan Timothy J Griffin

Institution:	(1) Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, 6-155 Jackson Hall, Minneapolis, Minnesota 55455, USA;(2) Oral Medicine, Diagnosis and Radiology, School of Dentistry, University of Minnesota, 515 Delaware St SE, Minneapolis, Minnesota, 55455, USA;(3) Minnesota Supercomputing Institute, University of Minnesota, 117 Pleasant Street SE, Minneapolis, Minnesota 55455, USA

Abstract:	Introduction Early diagnosis of Oral Squamous Cell Carcinoma (OSCC) increases the survival rate of oral cancer. For early diagnosis, molecular biomarkers contained in samples collected non-invasively and directly from at-risk oral premalignant lesions (OPMLs) would be ideal.

Keywords:	Oral Pre-Malignant Lesion (OPML) Oral Squamous Cell Carcinoma (OSCC) exudate mass spectrometry-based proteomics biomarker
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