Abstract: | EPSPs of rubrospinal neurons evoked by stimulation of the sensorimotor area of the cortex were studied in cats anesthetized with pentobarbital by means of intracellular recording. The involvement of corticospinal input in generating the EPSP was assessed by selective activation of corticospinal fibers at medullary pyramid level and by studying how they interact under the effects of cortical stimulation. It was shown that predominantly corticospinal and corticorubral neurons with slow-conducting axons are involved equally in the genesis of the first two components of complex EPSP. The cellular composition and mechanisms of corticofugal influences on red nucleus neurons are discussed.L. A. Orbeli Institute of Physiology, Academy of Sciences of the Armenian SSR, Erevan. Translated from Neirofiziologiya, Vol. 17, No. 5, pp. 692–700, September–October, 1985. |