| 新型抗肿瘤药DIDOX及其类似物的合成 |
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| 引用本文： | 邵航. 新型抗肿瘤药DIDOX及其类似物的合成[J]. 氨基酸和生物资源, 1996, 18(2): 25-26 |
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| 作者姓名： | 邵航 |
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| 作者单位： | 山东师范大学外语系，山东省中医院，山东医科大学药学系 |
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| 摘 要： | 通过酯化、氨解等反应，合成了抗癌新药ＤＩＤＯＸ（３，４－二羟荃苯并氧肟酸）及其五个类似物，并用ＩＲ证实了其结特征［１－３］。
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| 关 键 词： | 抗肿瘤药物，DIDOX，合成 |
Synthesis of New Antineoplastic DIDOX And It's Analogues |
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| Shao Hong, Liu Chunxiang et al. Synthesis of New Antineoplastic DIDOX And It's Analogues[J]. Amino Acids & Biotic Resources, 1996, 18(2): 25-26 |
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| Authors: | Shao Hong Liu Chunxiang et al |
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| Affiliation: | ,Shao Hong, Liu Chunxiang et al(Department of Pharmacology Shandong Medical niversity.Jinan,25001 2) |
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| Abstract: | The esterification of 3, 4-dihydroxybenzoin acid with refluxing methanol and H2SO4 gives the corresponding methyl ester, which is then treated with hydroxylamine in water containing NaOH. |
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| Keywords: | Antineoplastic DIDOX Synthesis |
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