Glycogenin: the primer for mammalian and yeast glycogen synthesis |
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Authors: | Lomako Joseph Lomako Wieslawa M Whelan William J |
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Institution: | Department of Biochemistry and Molecular Biology, University of Miami School Medicine, Miami, FL 33136, USA. |
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Abstract: | Glycogen synthesis, whether in mammalian tissue, yeast, or Agrobacterium tumefaciens or other bacteria, is initiated by autoglucosylation of a protein. Initiation in muscle, by a self-glucosylating protein, glycogenin-1, is the most thoroughly studied system, as is described here. These relatively recent findings have prompted a rekindling of interest in the intermediates lying between the primer and mature mammalian glycogen. |
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