A model for replication of the ends of linear chromosomes |
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| Authors: | John M Heumann |
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| Institution: | Department of Molecular, Cellular, & Developmental Biology, University of Colorado, Boulder, CO 80302, USA |
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| Abstract: | Linear chromosomes possessing internal repeats of their terminal sequences can form intramolecular crossed-strand exchanges that allow replication of the chromosome ends. Evidence is discussed that such a mechanism may be utilized during replication of herpes simplex virus DNA and during replication of macronuclear DNA from the hypotrichous ciliate Oxytricha. |
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