Inhibition of testicular luteinizing hormone receptor level by treatment with a potent luteinizing hormone-releasing hormone agonist of human chorionic gonadotropin. |
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| Authors: | C Auclair P A Kelly F Labrie D H Coy A V Schally |
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| Affiliation: | Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110 USA |
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| Abstract: | Two proteins larger than proinsulin (estimated molecular weight 11,000 and 10,000 daltons), were observed when labeled rat islet proteins were electrophoresed on sodium dodecyl sulfate gels. The proteins are synthesized before proinsulin, turn over more rapidly than proinsulin, their synthesis is stimulated by glucose, and they are specifically bound by anti-insulin antibodies. |
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| Keywords: | mRNA messenger ribonucleic acid sodium dodecyl sulfate M.W. molecular weight PPO 2,5′diphenyloxazole AIS anti-insulin serum |
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