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双歧杆菌DM-8504活菌制剂预防化疗引起的腹泻疗效观察
引用本文:刘基巍,周涛,张洁,陈亚敏,蔡欣.双歧杆菌DM-8504活菌制剂预防化疗引起的腹泻疗效观察[J].中国微生态学杂志,2000,12(3):178-179.
作者姓名:刘基巍  周涛  张洁  陈亚敏  蔡欣
作者单位:大连医科大学第一临床学院,肿瘤科,辽宁,大连,116011
基金项目:省教委科题!双歧杆菌 DM— 85 0 4抗肿瘤临床作用
摘    要:22例肿瘤化疗患者采用随机对照交叉试验,对照组采用单纯化疗实验组采用化疗+双歧杆菌活菌制剂。结果显示双歧杆菌活菌制剂可预防化疗引起的腹泻(对照组腹泻率45.5%,实验组为27.3%),并可改善腹珠反应程度(重度腹泻率对照组为18.2%,初级组为4.5%),有统计学差异(P〈0.01),提示双歧杆菌活菌制剂预防化疗引起的腹泻疗效确切。

关 键 词:双歧杆菌  腹泻  DM-8504活菌制剂  预防
修稿时间:2000-04-15

PROPHALYXIS OF CHEMOTHERAPY-INDUCED DIARREA BY BIFIDOBACTERIUM AGENT
LIU Ji wei,ZHOU Tao,ZHANG Jie,et al..PROPHALYXIS OF CHEMOTHERAPY-INDUCED DIARREA BY BIFIDOBACTERIUM AGENT[J].Chinese Journal of Microecology,2000,12(3):178-179.
Authors:LIU Ji wei  ZHOU Tao  ZHANG Jie  
Abstract:cancer patients were auto-across-contrl randomised into test group (chemotherapy Bifidobacterium agent), and control group (chemotherapy only). Prophalyxis of chemotherapy-induced diarrea by Bifidobacterium agent was effctive (diarrea 45.5% in control group, 27.3% in test group), and reduced grades of diarrea (heavy diarrea 18.2% in control group, 4.5 in test group), significantly different(P<0.01), indicating that Prophalyxis of chemotherapy-induced diarrea by Bifidobacterium agent was confirmed.
Keywords:bifidobacterium  chemotherapy  diarrea  
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