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| Authors: | Mårten Kivi Sandra Rodin Ilya Kupershmidt Annelie Lundin Ylva Tindberg Marta Granström Lars Engstrand |
| Affiliation: | (1) Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 171 77 Stockholm, Sweden;(2) Department of Bacteriology, Swedish Institute for Infectious Disease Control (SMI),, 171 82 Solna, Sweden;(3) Department of Biotechnology, Royal Institute of Technology (KTH), 100 44 Stockholm, Sweden;(4) Agilent Technologies, 395 Page Mill Rd, Palo Alto, CA 4306, USA;(5) Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, 171 77 Stockholm, Sweden |
| Abstract: | BackgroundHelicobacter pylori infection is exceptionally prevalent and is considered to be acquired primarily early in life through person-to-person transmission within the family. H. pylori is a genetically diverse bacterial species, which may facilitate adaptation to new hosts and persistence for decades. The present study aimed to explore the genetic diversity of clonal isolates from a mother and her three children in order to shed light on H. pylori transmission and host adaptation. |
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