Determination of N-Acetylaspartic Acid in Human Cerebrospinal Fluid by Gas Chromatography–Mass Spectrometry |
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Authors: | Carl-Gunnar Swahn |
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Affiliation: | Department of Psychiatry and Psychology, Karolinska Institutet, Stockholm, Sweden. |
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Abstract: | N-Acetyl-L-aspartic acid was identified and determined in human cerebrospinal fluid. The concentration in lumbar fluid was about 2 nmol/ml and about 20 nmol/ml in ventricular fluid. There was no difference between healthy subjects and schizophrenic patients. |
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Keywords: | N-Acetylaspartic acid Cerebrospinal fluid Gas chromatography-mass spectrometry Schizophrenia |
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