Spotting the mistakes, one molecule at a time |
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Authors: | Audrey Quessada-Vial Antoine M van Oijen |
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Affiliation: | Zernike Institute for Advanced Materials, Groningen University, Nijenborgh 4, 9747 AG Groningen, The Netherlands. |
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Abstract: | In this issue of Structure, Cho and colleagues provide intriguing insight into the first steps of the DNA mismatch repair process. By using single-molecule techniques, they show that the protein MutS undergoes two different types of diffusion on error-containing DNA in an ATP-dependent way. |
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