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The role of DOT1L in the maintenance of leukemia gene expression
Affiliation:1. Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;2. Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA;1. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;2. Weatherall Institute of Molecular Medicine, Molecular Haematology Unit, NIHR Oxford Biomedical Research Centre Programme, University of Oxford, Headington, Oxford OX3 9DS, UK;3. Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga 840-8502, Japan;4. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;5. Cancer and Blood Diseases Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA;6. Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA;7. Department of Biochemistry, Molecular and Cell Biology, University of Zaragoza, 50018 Zaragoza, Spain;8. Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;9. Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland;10. German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany;11. Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;12. Department of Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA;1. Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA;2. Department of Biology, Stanford University, Stanford, CA 94305, USA;3. Pediatrics and Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA;4. Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;5. Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA;1. Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, 430079, PR China;2. Structural Genomics Consortium, University of Toronto, Toronto, Ontario, M5G 1L7, Canada;3. Department of Physiology, University of Toronto, Toronto, Ontario, M5S 1A8, Canada;1. Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa 920-1192, Ishikawa, Japan;2. Molecular Therapeutic Target Research Unit, Institute for Frontier Science Initiative (InFIniti), Kanazawa University, Kanazawa 920-1192, Ishikawa, Japan
Abstract:
Keywords:
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