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Preferential replication-dependent mutagenesis in the lagging DNA strand inEscherichia coli
Authors:T. Iwaki   K. Kohno   Y. Kano   N. Goshima   F. Imamoto   A. Kawamura   Y. Ishino   M. Yara   M. Furusawa  H. Doi
Affiliation:(1) Department of Molecular Genetics, Institute of Molecular and Cellular Biology for Pharmaceutical Sciences, Kyoto Pharmaceutical University, 1, Shichono-cho, Misasagi, Yamashina-ku, 607 Kyoto, Japan;(2) Biotechnology Research Laboratories, Takara Shuzo Co. Ltd., 4-1 Seta 3-chome, 520-21 Otsu, Shiga, Japan;(3) Molecular Biology Research Laboratory, Daiichi Pharmaceutical Co. Ltd., 16-13 Kitakasai 1-chome, Edogawa-ku, 134 Tokyo, Japan;(4) Biological Informatics Section, IIAS, Fujitsu Laboratories Ltd., 9-3 Nakase 1-chome, Mihama-ku, 261 Chiba, Japan;(5) Present address: Department of Molecular Biology, Biomolecular Engineering Research Institute, 6-2-3, Furuedai, Suita, 565 Osaka, Japan
Abstract:
Keywords:Asymmetrical mutagenesis  dnaQ49  mutator  Preferential lagging strand mutagenesis  Frameshift reversion
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