Developmental mutants ofStreptomyces coeruleorubidus,a producer of anthracyclines: Isolation and preliminary characterization |
| |
Authors: | M. Blumauerová V. Pokorný J. Šťastná Z. HoŠťálek Z. Vaněk |
| |
Affiliation: | (1) Department of Biogenesis of Natural Substances, Czechoslovak Academy of Sciences, 142 20 Prague 4;(2) Department of Molecular Biology and Genetics Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20 Prague 4 |
| |
Abstract: | Abstbact The wild strainStreptomyces coeruleorubidus JA 10092 was found to segregate into two spontaneous morphological variants (spo-1 andbld-1) with a different ability to form aerial mycelium in media with glucose as the main carbon source. Six new types of developmental mutants were obtained from the bald variantbld-1 after treatment with mutagens (UV light, γ radiation, nitrous acid) and after natural selection Formation of the aerial mycelium was fully suppressed in thebld-2 type growing on media both with glucose and with starch. The other types were bald only on starch media, forming the aerial mycelium on media with glucose; typesspo-2, spo-3, spo-4 andspo-5 differed in size, shape and surface structure of spores, the typewhi formed asporogenous aerial hyphae. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|