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Second-Shell Basic Residues Expand the Two-Metal-Ion Architecture of DNA and RNA Processing Enzymes |
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| Authors: | Vito Genna Matteo Colombo Marco De Vivo Marco Marcia |
| Affiliation: | 1. Laboratory of Molecular Modelling & Drug Discovery, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy;2. European Molecular Biology Laboratory, Grenoble Outstation, 71 Avenue des Martyrs, Grenoble 38042, France;3. IAS-5/INM-9 Computational Biomedicine Forschungszentrum Jülich, Wilhelm-Johnen-Straße, 52428 Jülich, Germany |
| Abstract: |  |
| Keywords: | ribozymes splicing gene editing DNA/RNA polymerases enzyme engineering molecular simulations molecular dynamics metalloenzyme |
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