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Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis
Authors:Lee  Yoon-Jin  Nam   Hae-Seon  Cho   Moon-Kyun  Lee   Sang-Han
Affiliation:1.Department of Cardiology, The Third Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, 600 Tianhe, Guangzhou, 510630, Guangdong, China
;2.Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, Guangdong, China
;3.Department of Endocrinology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, Guangdong, China
;4.Institute Integrated Traditional Chinese and Western Medicine, Sun Yat-sen University, Guangzhou, 510630, Guangdong, China
;
Abstract:Molecular and Cellular Biochemistry - Adipose tissue inflammation is closely associated with the development of obesity and insulin resistance. Free fatty acids (FFAs) are a major inducer of...
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