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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis |
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| Authors: | Christopher D Wiley Rishi Sharma Sonnet S Davis Jose Alberto Lopez-Dominguez Kylie P Mitchell Samantha Wiley Fatouma Alimirah Dong Eun Kim Therese Payne Andrew Rosko Eliezer Aimontche Sharvari M Deshpande Francesco Neri Chisaka Kuehnemann Marco Demaria Arvind Ramanathan Judith Campisi |
| Institution: | 1. Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA;2. Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA;3. European Research Institute for the Biology of Aging (ERIBA), University Medical Center Groningen (UMCG), Antonius Deusinglaan 1, 9713 Groningen, the Netherlands;4. Institute for Stem Cell Science and Regenerative Medicine, GKVK - Post, Bellary Road, Bengaluru, Karnataka 560065, India;5. Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA |
| Abstract: |  |
| Keywords: | cellular senescence senescence aging lipids metabolomics eicosanoid SASP prostaglandin dihomo-prostaglandin biomarker mass spectrometry 15d-PGJ2 oxylipin RAS |
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