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C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly
Authors:Tao Wang  Honghe Liu  Kie Itoh  Sungtaek Oh  Liang Zhao  Daisuke Murata  Hiromi Sesaki  Thomas Hartung  Chan Hyun Na  Jiou Wang
Affiliation:1. Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA;2. Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA;3. Department of Cell Biology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA;4. Department of Neurology, Institute for Cell Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA;5. Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Abstract:
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  • Keywords:C9orf72  complex I  mitochondrion  oxidative phosphorylation  mitochondrial import  neurodegeneration  TIMMDC1  ALS  FTD  OXPHOS
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