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Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism
Authors:Diba Borgmann  Elisa Ciglieri  Nasim Biglari  Claus Brandt  Anna Lena Cremer  Heiko Backes  Marc Tittgemeyer  F. Thomas Wunderlich  Jens C. Brüning  Henning Fenselau
Affiliation:1. Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany;2. Translational Neurocircuitry Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany;3. Center for Anatomy II, Neuroanatomy, University Hospital Cologne, Joseph-Stelzmann Str. 9, 50937 Cologne, Germany;4. Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50937 Cologne, Germany;5. Max Planck Institute for Metabolism Research, Department of Neuronal Control of Metabolism, Gleueler Strasse 50, 50931 Cologne, Germany;6. Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Straße 26, Cologne 50931, Germany;7. Center of Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Straße 21, 50931 Cologne, Germany
Abstract:
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  • Keywords:gut-brain axis  sensory neurons  vagus nerve  glucose metabolism  chemogenetics  Dre-recombinase  intersectional genetics  nodose ganglion  dorsal root ganglion  appetite
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