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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
Authors:Yi-Ping Wang  Azeem Sharda  Shuang-Nian Xu  Nick van Gastel  Cheuk Him Man  Una Choi  Wei Zhong Leong  Xi Li  David T Scadden
Institution:1. Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA;2. Harvard Stem Cell Institute, Cambridge, MA 02138, USA;3. Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA;4. Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, Key Laboratory of Breast Cancer in Shanghai, Cancer Institute, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College, Fudan University, Shanghai 20032, China;5. Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 20032, China;6. Department of Hematology, Southwest Hospital, Army Medical University, Chongqing 400038, China
Abstract:
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  • Keywords:malic enzyme 2  fumarate  deoxyuridine 5′-triphosphate nucleotidohydrolase  mitochondrial ribosome protein L45  mitochondrial ribosome  arginine methylation  protein arginine methyltransferase 1  mitobiogenesis  acute myeloid leukemia
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