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Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
Authors:Jery Joy  Lara Barrio  Celia Santos-Tapia  Daniela Romão  Nikolaos Nikiforos Giakoumakis  Marta Clemente-Ruiz  Marco Milán
Affiliation:1. Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain;2. Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluís Companys 23, 08010 Barcelona, Spain
Abstract:
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  • Keywords:aneuploidy  proteotoxic stress  mitochondrial dysfunction  tissue repair  autophagy  mitophagy  senescence  chromosomal instability
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