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Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health
Authors:Joji Kusuyama  Ana Barbara Alves-Wagner  Royce H. Conlin  Nathan S. Makarewicz  Brent G. Albertson  Noah B. Prince  Shio Kobayashi  Chisayo Kozuka  Magnus Møller  Mette Bjerre  Jens Fuglsang  Emily Miele  Roeland J.W. Middelbeek  Yang Xiudong  Yang Xia  Léa Garneau  Jayonta Bhattacharjee  Céline Aguer  Laurie J. Goodyear
Affiliation:1. Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA;2. Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Miyagi, Japan;3. Section of Immunobiology, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA;4. YCI Laboratory for Metabolic Epigenetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan;5. Department of Gynecology and Obstetrics, Aarhus University Hospital and Clinical Institute, Aarhus University, Aarhus, Denmark;6. Medical Research Laboratory, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark;7. Graduate School of Biomedical Sciences, University of Texas at Houston, Houston, TX, USA;8. Institut du Savoir Montfort, recherche, Ottawa, Canada;9. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada;10. School of Human Kinetics, Faculty of Health Science University of Ottawa, Ottawa, Canada;11. Interdisciplinary School of Health Sciences, Faculty of Health Science University of Ottawa, Ottawa, Canada;12. Steno Diabetes Center Aarhus, Department of Biomedicine, Aarhus University, Aarhus, Denmark;13. Department of Anatomy, Kanazawa Medical University, Ishikawa, Japan;14. Cardiovascular Pulmonary Research Laboratories and Pediatric Critical Care, Department of Pediatrics, University of Colorado Anschutz Medical Center, Aurora, CO, USA
Abstract:
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  • Keywords:maternal exercise  placenta  DNA methylation  pregnancy  glucose metabolism  superoxide dismutase 3  vitamin D  TET  AMPK
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