| 植物SUMO化修饰及其生物学功能 |
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| 引用本文： | 徐庞连,曾棉炜,黄丽霞,阳成伟.植物SUMO化修饰及其生物学功能[J].植物学通报,2008,25(5):608-615. |
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| 作者姓名： | 徐庞连 曾棉炜 黄丽霞 阳成伟 |
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| 作者单位： | 华南师范大学生命科学学院,广东省植物发育生物工程重点实验室,广州,510631 |
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| 基金项目： | 国家自然科学基金，广东省科技攻关计划 |
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| 摘 要： | SUMO化修饰是细胞内蛋白质功能调节的重要方式之一。植物中的SUMO化修饰途径由SUMO分子和SUMO化酶系组成。SUMO化修饰是一个可逆的动态过程。SUMO前体蛋白在SUMO特异性蛋白酶的作用下成熟，随后通过SUMO活化酶、SUMO结合酶和SUMO连接酶将靶蛋白SUMO化，最后SUMO特异性蛋白酶将SUMO与靶蛋白分离，重新进入SUMO化循环。初步研究表明，植物SUMO化修饰参与植物花期调控、激素信号转导、抗病防御以及逆境应答等生理过程。
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| 关 键 词： | 生长发育 植物 胁迫 SUMO化修饰 |
SUMOylation and Its Biological Function in Plants |
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| Panglian Xu,Mianwei Zeng,Lixia Huang,Chengwei Yang.SUMOylation and Its Biological Function in Plants[J].Chinese Bulletin of Botany,2008,25(5):608-615. |
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| Authors: | Panglian Xu Mianwei Zeng Lixia Huang Chengwei Yang |
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| Institution: | ( Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, College of Life Sciences, South China Normal University, Guangzhou 510631, China) |
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| Abstract: | Post-translational modification by small ubiquitin-related modifiers （SUMOs） is an important regulatory process to modulate protein function. This paper summarizes the SUMOylation pathway in plants; the pathway consists of SUMO molecules, a SUMO conjugation enzyme cascade and de-conjugation enzymes. Nascent SUMOs are processed by SUMO-specific proteases, then mature SUMOs are conjugated to substrate proteins by sequential action of three groups of enzymes： SUMO-activating enzymes （E1）, SUMO-conjugating enzymes （E2） and SUMO-ligating enzymes （E3）. SUMOylation can be reversed by SUMO-specific proteases. SUMO modification in plants is involved in flowering induction, hormone signaling, pathogen defense and stress response. |
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| Keywords: | growth and development plant stress SUMOylation |
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