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拟南芥AtMEKK1的结构特征和信号转导功能
引用本文:周严,刘玉鲲,孔祥培,李德全. 拟南芥AtMEKK1的结构特征和信号转导功能[J]. 植物生理学通讯, 2011, 0(4): 339-346
作者姓名:周严  刘玉鲲  孔祥培  李德全
作者单位:山东农业大学生命科学学院作物生物学国家重点实验室;
基金项目:国家自然科学基金(30871457和31071337)
摘    要:促分裂原活化蛋白激酶(MAPK)级联途径是真核生物中高度保守的信号通路。MAPK级联途径由MAPKs、MAPKKs和MAPKKKs组成,通过MAPKKK→MAPKK→MAPK的逐级磷酸化传递细胞信号。AtMEKK1是拟南芥MAPKKK家族中的一员,是目前研究较为详细的MAPKKK。本文就AtMEKK1的结构特征、生理功能、信号转导中的"交谈"及其复杂性进行综述,旨在探讨植物MAPKKK的信号转导作用。

关 键 词:AtMEKK1  信号转导  信号特异性  MAPK级联途径

Structural Characteristics and Signal Transduction Functions of AtMEKK1 in Arabidopsis
ZHOU Yan,LIU Yu-Kun,KONG Xiang-Pei,LI De-Quan State Key Laboratory of Crop Biology,College of Life Sciences,Sh,ong Agricultural University,Tai'an,Sh,ong ,China. Structural Characteristics and Signal Transduction Functions of AtMEKK1 in Arabidopsis[J]. Plant Physiology Communications, 2011, 0(4): 339-346
Authors:ZHOU Yan  LIU Yu-Kun  KONG Xiang-Pei  LI De-Quan State Key Laboratory of Crop Biology  College of Life Sciences  Sh  ong Agricultural University  Tai'an  Sh  ong   China
Affiliation:ZHOU Yan,LIU Yu-Kun,KONG Xiang-Pei,LI De-Quan~* State Key Laboratory of Crop Biology,College of Life Sciences,Shandong Agricultural University,Tai'an,Shandong 271018,China
Abstract:Mitogen-activated protein kinase (MAPK) cascades constitute a conserved signaling pathway in eukaryotes. MAPK cascades consist of MAPKs, MAPKKs and MAPKKKs. MAPK cascades transduce signals by sequential phosphorylation (MAPKKK→MAPKK→MAPK). AtMEKK1 is one of the MAPKKKs in Arabidopsis and is the MAPKKK with detailed studies in plant. In this review, we summarized the structural characteristics and physiological functions of AtMEKK1. Furthermore, we discussed the "cross-talk" of AtMEKK1 with other signaling components and signal specificity. This review may shed light on the function of plant MAPKKKs.
Keywords:AtMEKK1  signal transduction  signal specificity  MAPK cascades  
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