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N-methyl-d-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain |
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| Authors: | Medeiros Priscila Negrini-Ferrari Sylmara Esther Palazzo Enza Maione Sabatino Ferreira Sérgio Henrique de Freitas Renato Leonardo Coimbra Norberto Cysne |
| Affiliation: | 1.Neuroscience Laboratory of Pain & Emotions and Multi-User Centre of Neuroelectrophysiology, Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Av. dos Bandeirantes, 3900, Ribeirão Preto, SP, 14049-900, Brazil ;2.Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. dos Bandeirantes, 3900, Ribeirão Preto, SP, 14049-900, Brazil ;3.Laboratory of Pain and Inflammation, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. dos Bandeirantes, 3900, Ribeirão Preto, SP, 14049-900, Brazil ;4.Department of Psychology, Ribeirão Preto School of Philosophy, Sciences and Literature of the University of São Paulo, Ribeirão Preto, SP, 14040-901, Brazil ;5.Biomedical Sciences Institute, Federal University of Alfenas (UNIFAL-MG), Str. Gabriel Monteiro da Silva, 700, Alfenas, MG, 37130-000, Brazil ;6.Division of Pharmacology, Department of Experimental Medicine, Universita degli Studi della Campania Luigi Vanvitelli, Naples, Italy ;7.Behavioural Neurosciences Institute (INeC), Av. do Café, 2450, Ribeirão Preto, SP, 14050-220, Brazil ; |
| Abstract: | Neurochemical Research - The mechanisms underlying chronic and neuropathic pain pathology involve peripheral and central sensitisation. The medial prefrontal cortex (mPFC) seems to participate in... |
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