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Disruption of cagA, the apoprotein gene of chromoprotein antibiotic C-1027, eliminates holo-antibiotic production, but not the cytotoxic chromophore
Authors:Zhihui Cui  Lifei Wang  Songmei Wang  Guangwei Li  & Bin Hong
Institution:Key Laboratory of Biotechnology of Antibiotics of Ministry of Health, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Abstract:
Keywords:C-1027  enediyne  apoprotein  gene disruption
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