Depression of steroid-induced sex behavior in the ovariectomized rat by intracranial injection of cycloheximide: Preoptic area compared to the ventromedial hypothalamus |
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| Authors: | J. Meinkoth D. M. Quadagno J. D. Bast |
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| Affiliation: | 1. Department of Physiology and Cell Biology, University of Kansas, Lawrence, Kansas 66045 U.S.A.;2. Departments of Anatomy and Gynecology/Obstetrics, R. L. Smith Research Center, University of Kansas Medical Center, Kansas City, Kansas 66103 U.S.A. |
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| Abstract: | Sexual receptivity was significantly depressed in the estrogen/progesteroneprimed, Ovariectomized rat after the bilateral injection of 5, 10, or 20 μg of cycloheximide (CHX) into either the preoptic area (POA) or ventromedial hypothalamus (VMH) 6 hr before the initiation of the steroid priming. There was no differential response to CHX, an inhibitor of protein synthesis, relative to the locus of the placement of the drug in either the POA or VMH. |
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| Keywords: | To whom requests for reprints should be sent. |
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