A Translocated Mitochondrial Cytochrome b Pseudogene in Voles (Rodentia: Microtus) |
| |
Authors: | J Andrew DeWoody Ronald K Chesser Robert J Baker |
| |
Institution: | (1) Department of Biological Sciences, Texas Tech University, US;(2) Savannah River Ecology Lab and Department of Genetics, University of Georgia, Athens, GA 30602, USA, US |
| |
Abstract: | A full-length cytochrome b pseudogene was found in rodents; it has apparently been translocated from a mitochondrion to the nuclear genome in the subfamily
Arvicolinae. The pseudogene (ψcytb) differed from its mitochondrial counterpart at 201 of 1143 sites (17.6%) and by four indels. Cumulative evidence suggests
that the pseudogene has been translocated to the nucleus. Phylogenetic reconstruction indicates that the pseudogene arose
before the diversification of M. arvalis/M. rossiaemeridionalis from M. oeconomus, but after the divergence of the peromyscine/sigmodontine/arvicoline clades some ∼10 MYA. Published rates of divergence between
mitochondrial genes and their nuclear pseudogenes suggest that the translocation of this mitochondrial gene to the nuclear
genome occurred some 6 MYA, in agreement with the phylogenetic evidence.
Received: 16 January 1998 / Accepted: 18 July 1998 |
| |
Keywords: | : mtDNA — Cytochrome b— Pseudogene — Microtus— Rodent — Translocation |
本文献已被 PubMed SpringerLink 等数据库收录! |