Some additional results about polymorphisms in models of an additive quantitative trait under stabilizing selection |
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Authors: | A. Gimelfarb |
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Affiliation: | (1) Department of Ecology and Evolution, The University of Chicago, 1101 East 57th Street, Chicago, Il 60637-1573, USA. e-mail: sashu@pondside.uchicago.edu, US |
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Abstract: | The existence of two stable, symmetric (allelic frequency 0.5 in each locus) polymorphic states is demonstrated for a two-locus model of an additive quantitative trait under strong Gaussian selection. Linkage disequilibrium at one of the states is negative whereas it is positive at the other state. For a three-locus model, it is shown that in order to maintain a stable polymorphism in all three loci, selection must be sufficiently but not exces- sively strong relative to recombination. Also, positive linkage disequilibrium can be maintained in a three-locus model under stabilizing selection that is not very strong. Received 15 July 1995 |
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Keywords: | : Multilocus systems Polymorphism Quantitative traits Stabilizing selection |
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