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Potent oxindole based human beta3 adrenergic receptor agonists |
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| Authors: | Stevens F Craig Bloomquist William E Borel Anthony G Cohen Marlene L Droste Christine A Heiman Mark L Kriauciunas Aidas Sall Daniel J Tinsley Frank C Jesudason Cynthia D |
| Affiliation: | Lilly Research Laboratories, Eli Lilly & Company, Lilly Corporate Center, Indianapolis, IN 46285, USA. |
| Abstract: | The synthesis and biological evaluation of a series of oxindole beta(3) adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety. |
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