Protein arrays for gene expression and molecular interaction screening |
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Authors: | Walter G Büssow K Cahill D Lueking A Lehrach H |
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Affiliation: | Biorchard AS, Oslo, N-0281, Norway. gerald@biorchard.com |
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Abstract: | The array format has revolutionised biomedical experimentation and diagnostics, enabling ordered high-throughput analysis. During the past decade, classic solid phase substrates, such as microtitre plates, membrane filters and microscopic slides, were turned into high-density, chip-like structures. The concept of the arrayed library was central to this development which now extends from DNA to protein. The new and versatile protein array technology allows high-throughput screening for gene expression and molecular interactions. As a major platform for functional genomics, it is already on its way into medical diagnostics. |
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