Modulation of Ca2+ dependent protease activity in fish and invertebrates by weak low-frequency magnetic fields

Results of experiments addressing the effects of weak low-frequency magnetic fields on intracellular Ca²⁺ dependent proteinases (calpains) from invertebrates and fish are discussed. Exposure of live animals to weak low-frequency magnetic fields with parameters chosen to induce the resonance of Ca²⁺ ions led to a significant decrease of calpain activity in the animals investigated. The physical factor studied also caused partial loss of activity in preparations of Ca²⁺ dependent proteinases obtained from invertebrates and fish. The phenomenon discovered is in accordance with the interference model of the effect of weak low-frequency magnetic fields on biological objects.