Strain-specific differences in pili formation and the interaction of Corynebacterium diphtheriae with host cells |
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| Authors: | Lisa Ott Martina Höller Johannes Rheinlaender Tilman E Schäffer Michael Hensel Andreas Burkovski |
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| Affiliation: | 1.Lehrstuhl für Mikrobiologie,Friedrich-Alexander-Universit?t Erlangen-Nürnberg,Nürnberg,Germany;2.Lehrstuhl für Angewandte Physik,Friedrich-Alexander-Universit?t Erlangen-Nürnberg,Nürnberg,Germany;3.Mikrobiologisches Institut des Universit?tsklinikums Erlangen,Erlangen,Germany;4.Abteilung Mikrobiologie,Universit?t Osnabrück,Osnabrück,Germany |
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| Abstract: | Background Corynebacterium diphtheriae, the causative agent of diphtheria, is well-investigated in respect to toxin production, while little is known about C. diphtheriae factors crucial for colonization of the host. In this study, we investigated strain-specific differences in adhesion, invasion and intracellular survival and analyzed formation of pili in different isolates. |
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