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Action of Candida rugosa lipase in carvone isomers as solvents
Authors:O. Ulbert  Á. Szarka  Sz. Halasi  B. Somogyi  K. Bélafi-bakó  L. Gubicza
Affiliation:(1) Department of Bioengineering, Pannon University of Agricultural Sciences, Research Institute of Chemical and Process Engineering, H-8201 Veszprém, P.O. Box 125, Hungary;(2) Department of Biophysics, Medical University School of Pécs, H-7601 Pécs, P.O. Box 99, Hungary;(3) Research Group of the Hungarian Academy of Sciences at the Department of Biophysics, Medical University School of Pécs, H-7601 Pécs, P.O. Box 99, Hungary
Abstract:The activity and enantioselectivity of Candida rugosa lipase were investigated in chiral solvents, (–)-, (+)- and racemic carvone, for the resolution of 2-chloro-propionic acid with n-butanol via esterification. The activity of the enzyme studied was about 50% higher in (–)-carvone than in (+)-carvone, however the enantioselectivity was similar.
Keywords:Candida rugosa lipase  chiral solvent  esterification
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