The effect of heat-stable extract from bovine sublingual salivary gland on serum cholesterol and triglyceride levels in normal and hypercholesterolemic rabbits |
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Authors: | H Omidfar Y Güven H Oz |
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Affiliation: | Department of Biochemistry, Istanbul Medical Faculty, University of Istanbul, Turkey. |
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Abstract: | An extract of bovine sublingual glands (SLF3) reduced the serum cholesterol levels of normal rabbits 34.6% and serum triglyceride levels 19.6% when injected intraperitoneally (i.p.) at 20 mg/kg body wt on alternate days for 7 days. SLF3 also reduced serum cholesterol levels 69.0% and triglyceride levels 46.5% in hypercholesterolemic rabbits, while in similar rabbits injected with a control muscle tissue extract, the rate of decrease in serum cholesterol levels was 33.3% and triglyceride levels 26.7%. |
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