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Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase,methylmalonyl-CoA mutase,and glutaminase fluxes in vivo
Affiliation:1. Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA;2. Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA;3. Department of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA;4. Departments of Psychiatry & Biomedical Engineering, Yale School of Medicine, New Haven, CT 06510, USA
Abstract:
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  • Keywords:metabolic flux analysis  mass spectrometry  anaplerosis  glutaminase  methylmalonyl-CoA mutase  succinate dehydrogenase  mitochondrial metabolism  insulin  glucagon  propionate
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