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Quantitative gene expression analysis on chromosome 6 between Korean native pigs and Yorkshire breeds for fat deposition |
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| Authors: | Xiaoping Li Cheol-Koo Lee Bong-Hwan Choi Tae-Hun Kim Jong-Joo Kim Kwan-Suk Kim |
| Affiliation: | 1. Department of Animal Science, Chungbuk National University, 12 Gaeshin-dong, Heungduk-ku, Cheongju, Chungbuk, 361-763, Korea 2. Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong (Central China) Agricultural University, Wuhan, 430070, Hubei, PR China 3. College of Life and Environmental Sciences, Korea University, Seoul, Korea 4. National Institute of Animal Science, Suwon, Korea 5. School of Biotechnology, Yeungnam University, Gyeongsan, Korea |
| Abstract: | Pig chromosome 6 (SSC6) has been reported to have QTL affecting backfat thickness (BFT) and intramuscular fat (IMF). A human-pig comparative map covering 18 autosomes with the highest resolution has been constructed and based on this map SSC6 has conserved syntenicgroups with human chromosome (HSA) 16, 19, 1, and 18. In this study, the pig Affy elements mapped to the SSC6 were analyzed, and the differentially expressed genes in three tissues (liver, backfat and loin muscle) between Yorkshire and Korean Native Pigs (KNP) were collected, in particular those genes located in the internal between markers SW1355 and SW1823 where a quantitative trait loci (QTL) affecting the intramuscular fat content (IMF) have been detected in multiple pig populations. The genes listed here may offer information for further study the candidate genes affecting these QTL on the expression level. |
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